AN300680L
Recombinant MECP2 Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300680L
- Additional Names:
- BMP,MECP,MRXS,DKFZp686A,Methyl-CpG-binding protein,AUTSX,MRX,MECP2,AUTSX3,MRX16,MRX79,MRXS13,MRXSL,PPMX,RS,RTS,RTT,DKFZp686A24160,MeCp-2 protein,Methyl-CpG-binding protein 2,BMP7,OP1,AUTSX 3,Mbd 5,Mbd5,MECP 2,MeCP 2 protein,Methyl CpG binding protein 2,Methyl CpG binding protein 2 (Rett syndrome),MRX 16,MRX 79,MRXS 13,WBP 10,WBP10
- Application:
- IHC, WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human MECP2 protein
- Clone:
- B619
- Uniprot:
- P51608
- Synonyms:
- AUTSX3;meCp-2 protein;methyl-CpG-binding protein 2;MRX16;MRX79;MRXS13;MRXSL;PPMX;RS;RTS;RTT
- Extra Details:
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
- Shipping Conditions:
- Blue Ice