AN300649L
Recombinant PKR Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300649L
- Additional Names:
- PPP1R,EIF2AK1,PKR,PPP1R83,PRKR,Eif2ak2,Double stranded RNA activated protein kinase,double-stranded RNA-activated protein kinase,E2AK2,eIF-2A protein kinase 2,Eukaryotic translation initiation factor 2 alpha kinase 2,Eukaryotic translation initiation factor 2-alpha kinase 2,HGNC:9437,Interferon induced double stranded RNA activated protein kinase,Interferon inducible elF2 alpha kinase,Interferon inducible RNA dependent protein kinase,Interferon-induced,Interferon-inducible RNA-dependent
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant Human PKR protein
- Clone:
- B584
- Uniprot:
- P19525
- Synonyms:
- double stranded RNA activated protein kinase;eIF-2A protein kinase 2;EIF2AK1;Eukaryotic translation initiation factor 2-alpha kinase 2;interferon-induced, double-stranded RNA-activated protein kinase;interferon-inducible elF2alpha kinase;Interferon-inducible RNA-dependent protein kinase;LEUDEN;P1/eIF-2A protein kinase;p68 kinase;PKR;PPP1R83;PRKR;protein kinase R;Protein kinase RNA-activated;protein kinase, interferon-inducible double stranded RNA dependent;protein phosphatase 1, regulatory subunit 83;tyrosine-protein kinase EIF2AK2
- Extra Details:
- The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice