AN300635L
Recombinant Phospho-Smad2, 3 (Thr8) Monoclonal Antibody
Size
£221.40
Was £246.00
- SKU:
- AN300635L
- Additional Names:
- MADH,MADR,hMAD,SMAD,hSMAD,JV18,JV18-1,MADH2,MADR2,hMAD-2,hSMAD2,Smad2,Drosophila,homolog of,hSMAD family member 2,JV181,MAD,MAD homolog 2,MAD Related Protein 2,Mad-related protein 2,MGC22139,MGC34440,Mother against DPP homolog 2,Mothers against decapentaplegic,Mothers against decapentaplegic homolog 2,Mothers against DPP homolog 2,OTTHUMP00000163489,Sma and Mad related protein 2,Sma- and Mad-related protein 2 MAD,SMAD 2,SMAD family member 2,Smad2/3
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- A synthetic peptide corresponding to residues around (Thr8) of Human Phospho-Smad2, 3
- Clone:
- B570
- Uniprot:
- P84022, Q15796
- Synonyms:
- hMAD-2;hMAD-3;hSMAD2;hSMAD3;HSPC193;HsT17436;JV15-2;JV18;JV18-1;LDS1C;LDS3;MAD homolog 2;MAD homolog 3;mad homolog JV15-2;mad protein homolog;Mad-related protein 2;MAD, mothers against decapentaplegic homolog 3;mad3;MADH2;MADH3;MADR2;mother against DPP homolog 2;mothers against decapentaplegic homolog 2;mothers against decapentaplegic homolog 3;mothers against DPP homolog 3;Sma- and Mad-related protein 2;SMA- and MAD-related protein 3;SMAD family member 2;SMAD family member 3;SMAD, mothers against DPP homolog 2;SMAD, mothers against DPP homolog 3
- Extra Details:
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene &apos,mothers against decapentaplegic&apos, (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4.
- Shipping Conditions:
- Blue Ice