AN300582P
Recombinant Neurexophilin-1/NXPH1 Monoclonal Antibody
Size
£361.80
Was £402.00
- SKU:
- AN300582P
- Additional Names:
- Nph,MGC,NXPH,MGC124635,Nph1,Nxph1
- Application:
- IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Rat
- Buffer:
- PBS
- Immunogen:
- Recombinant Rat Neurexophilin-1/NXPH1 protein
- Clone:
- B517
- Uniprot:
- Q63366
- Synonyms:
- neurexophilin-1;neurophilin
- Extra Details:
- Neurexophilin-1 or NXPH1 is a secreted glycoprotein, which belongs to the Neurexophilin family. The Neurexophilin family contains at least four genes and resembles a neuropeptide, suggesting a function as an endogenous ligand for alpha-neurexins. The mammalian brains contain four genes for neurexophilins the products of which share a common structure composed of five domains: an N-terminal signal peptide, a variable N-terminal domain, a highly conserved central domain that is N-glycosylated, a short linker region, and a conserved C-terminal domain that is cysteine-rich. Neurexophilin-1 constitutes a secreted cysteine-rich glycoprotein, forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. Neurexophilins 1 and 3 but not 4 (neurexophilin 2 is not expressed in rodents) bind to a single individual LNS domain, the second overall LNS domain in all three alpha-neurexins.
- Shipping Conditions:
- Blue Ice