Recombinant CD79B/Ig-beta Monoclonal Antibody

Size

£361.80

Was £402.00

SKU:: AN300556P
Additional Names:: B-Cell-Specific Glycoprotein B,B29,B-Cell Antigen Receptor Complex-Associated Protein Beta Chain,B-Cell-Specific Glycoprotein B29,Igbeta,Ig-beta,Immunoglobulin-Associated B29 Protein,Igb,Cd79b,B29,Ig&amp,beta
Application:: IHC-P
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: Recombinant Mouse CD79B/Ig-beta Protein
Clone:: B486
Uniprot:: P15530
Synonyms:: B-cell antigen receptor complex-associated protein beta chain;B-cell-specific glycoprotein B29;B29;Ig;Ig-be;Ig-beta;Igb;Igbe;Igbeta;immunoglobulin-associated B29 protein;immunoglobulin-associated beta
Extra Details:: CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258, 1375264, 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).