Recombinant LY9/CD229/SLAMF3 Monoclonal Antibody

Size

£361.80

Was £402.00

SKU:: AN300526P
Additional Names:: Ly-9,Ly9
Application:: Flow Cytometry, IF, ICC
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: Recombinant Mouse LY9/CD229/SLAMF3 protein
Clone:: B456
Uniprot:: Q01965
Synonyms:: AI893573;CD229;cell surface molecule Ly-9;Lgp1;Lgp100;Ly-9;Lymphocyte antigen 9;signaling lymphocytic activation molecule 3;SLA;SLAM family member 3;SLAMF3;T-lymphocyte surface antigen Ly-9;T100
Extra Details:: Signaling lymphocytic activation molecule 3 (SLAMF3), also known as CD229 or Ly9, is a type I transmembrane glycoprotein that belongs to the SLAM family receptors (PMID: 10970093, 15905546). It is composed of an extracellular region, which consists of four Ig-like domains, a transmembrane region, and a cytoplasmic tail, which includes two immunoreceptor tyrosine-based signaling motifs (ITSMs) and other tyrosine residues that act as binding sites for the SH2 structural domains (PMID: 8537117, 11369645, 38626547). SLAMF3 is mainly expressed in immune cells, such as T, B, and natural killer cells, and it is involved in the fundamental activation and suppression of these immune cells, as well as the regulation of complex immune networks (PMID: 38626547).