Recombinant Gastric intrinsic factor/GIF Monoclonal Antibody

Size

£361.80

Was £402.00

SKU:: AN300441P
Additional Names:: TCN,IF,INF,TCN3,Transcobalamin III,Vitamin B Synthesis,GIF,IFMH,CBLIF
Application:: WB, IP
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS
Immunogen:: Recombinant Human Gastric intrinsic factor/GIF Protein
Clone:: B367
Uniprot:: P27352
Synonyms:: cobalamin binding intrinsic factor;gastric intrinsic factor (vitamin B synthesis);GIF;IF;IFMH;INF;intrinsic factor;TCN3
Extra Details:: Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to gastric intrinsic factor. This new complex travels to the ileum, where special epithelial cells endocytose them. Inside the cell, B12 dissociates once again and binds to another protein, transcobalamin II. The new complex can exit the epithelial cells to enter the liver.