AN300424P
Recombinant Thioredoxin-2/TXN2 Monoclonal Antibody
Size
£361.80
Was £402.00
- SKU:
- AN300424P
- Additional Names:
- TRX,TXN,Thioredoxin,MTRX,Mt-Trx,Thioredoxin Mitochondrial,Thioredoxin-2,TRX2,TXN2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human Thioredoxin-2/TXN2 protein
- Clone:
- B350
- Uniprot:
- Q99757
- Synonyms:
- COXPD29;mitochondrial thioredoxin;MT-TRX;MTRX;Thioredoxin-2;thioredoxin, mitochondrial;TRX2;TXN
- Extra Details:
- Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2/TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2/TXN2 is a small redox protein important in cellular antioxidant defenses, as well as in the regulation of apoptosis. Thioredoxin-2/TXN2 has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Thioredoxin-2/TXN2 could be involved in the resistance to anti-tumor agents. It possesses a dithiol-reducing activity. Thioredoxin-2/TXN2 plays an important role in protecting the mitochondria against oxidative stress and in sensitizing the cells to ROS-induced apoptosis. Mammalian Thioredoxin-2/TXN2 is a mitochondrial isoform of highly evolutionary conserved thioredoxins. Thioredoxins are small ubiquitous protein-disulfide oxidoreductases implicated in a large variety of biological functions.
- Shipping Conditions:
- Blue Ice