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AN300414P

Recombinant PNP Monoclonal Antibody

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£361.80

Was £402.00

SKU:
AN300414P
Additional Names:
PRO,PNP,NP,PRO1837,PUNP
Application:
IHC-P
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS
Immunogen:
Recombinant Human PNP protein
Clone:
B340
Uniprot:
P00491
Synonyms:
epididymis secretory sperm binding protein Li 156an;HEL-S-156an;inosine phosphorylase;inosine-guanosine phosphorylase;NP;PRO1837;PUNP;purine nucleoside phosphorylase;purine-nucleoside:orthophosphate ribosyltransferase
Extra Details:
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.
Shipping Conditions:
Blue Ice