AN300226P
Recombinant REG4 Monoclonal Antibody
Size
£361.80
Was £402.00
- SKU:
- AN300226P
- Additional Names:
- REG,Regenerating islet-derived protein,REG4,GISP,REG-IV,RELP,Gastrointestinal secretory protein,Regenerating islet-derived protein 4,Regenerating islet-derived protein IV,REG-like protein,regenerating family member 4
- Application:
- IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human REG4 Protein
- Clone:
- B144
- Uniprot:
- Q9BYZ8
- Synonyms:
- gastrointestinal secretory protein;GISP;reg IV;REG-4;REG-IV;REG-like protein;regenerating gene type IV;regenerating islet-derived family, member 4;regenerating islet-derived protein 4;regenerating islet-derived protein IV;RELP
- Extra Details:
- Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
- Shipping Conditions:
- Blue Ice