Recombinant Fractalkine/CX3CL1 Monoclonal Antibody

Size

£170.10

Was £189.00

SKU:: AN300199P
Additional Names:: CXC,ABCD,SCYD,IGHG,C-X3-C Motif Chemokine,Small-Inducible Cytokine D,CX3CL,A-152E,CX3CL1,ABCD-3,C3Xkine,CXC3,CXC3C,NTN,NTT,SCYD1,fractalkine,CX3C Membrane-Anchored Chemokine,C-X3-C Motif Chemokine 1,Neurotactin,Small-Inducible Cytokine D1,IGHG3,FKN,A-152E5.2,Fractalkine
Application:: IHC-P
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS
Immunogen:: Recombinant Human Fractalkine / CX3CL1 protein
Clone:: B117
Uniprot:: P78423
Synonyms:: ABCD-3;C-X3-C motif chemokine 1;C3Xkine;chemokine (C-X3-C motif) ligand 1;CX3C membrane-anchored chemokine;CXC3;CXC3C;fractalkine;neurotactin;NTN;NTT;SCYD1;small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin);small inducible cytokine subfamily D (Cys-X3-Cys), member-1;small-inducible cytokine D1
Extra Details:: This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections.

Shipping Conditions:: Blue Ice