Recombinant IL3RA/CD123 Monoclonal Antibody

Size

£361.80

Was £402.00

SKU:: AN300195P
Additional Names:: IL3RA,CD123,IL3R,IL3RAY,IL3RX,IL3RY,hIL-3Ra,IL-3 Receptor alpha,IL-3 receptor subunit alpha,IL-3R subunit alpha,IL-3R subunitalpha,IL-3RA,IL-3R-alpha,IL-3Receptoralpha,IL-3RA Alpha,IL-4Receptoralpha,IL-5Receptoralpha,IL-6Receptoralpha,IL-7Receptoralpha,Interleukin-3 receptor subunit alpha,IL-3R&amp,alpha
Application:: WB, IP
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS
Immunogen:: Recombinant Human IL3RA protein
Clone:: B113
Uniprot:: P26951
Synonyms:: CD123;CD123 antigen;hIL-3Ra;IL-3 receptor subunit alpha;IL-3R subunit alpha;IL-3R-alpha;IL-3RA;IL3R;IL3RAY;IL3RX;IL3RY;interleukin 3 receptor, alpha (low affinity);interleukin-3 receptor subunit alpha
Extra Details:: CD123 is the 70 kD transmembrane A Alpha chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity, when CD123 associates with CDw131 (common B Beta chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the B Beta chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.