AN300148L
Recombinant Phospho-PLCG Gamma1 (Tyr783) Monoclonal Antibody
Size
£170.10
Was £189.00
- SKU:
- AN300148L
- Additional Names:
- PLCG,phospholipase C gamma,NCKAP,PLCgamma,PLC,PLCG1,NCKAP3,PLC-II,PLC1,PLC148,PLCgamma1,phospholipase C gamma 1,NCKAP3,phospholipase C gamma 1,PLC1,PLC148,PLCgamma1,PLC-II
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 10 mM sodium HEPES, 150 mM NaCl, 100 ug/mL protein protectant, 50% glycerol, pH 7.5
- Immunogen:
- A synthetic phosphopeptide corresponding to residues around Tyr783 of the Human PLCG Gamma1
- Clone:
- A1262
- Uniprot:
- P19174
- Synonyms:
- 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;inositoltrisphosphohydrolase;monophosphatidylinositol phosphodiesterase;NCKAP3;phosphatidylinositol phospholipase C;phosphoinositidase C;phosphoinositide phospholipase C;phosphoinositide phospholipase C-gamma-1;phospholipase C-148;Phospholipase C-gamma-1;phospholipase C-II;phospholipase C, gamma 1 (formerly subtype 148);PLC-148;PLC-gamma-1;PLC-II;PLC1;PLC148;PLCgamma1;triphosphoinositide phosphodiesterase
- Extra Details:
- The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 2 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice