Recombinant Olig-2/Oligo2 Monoclonal Antibody

Size

£170.10

Was £189.00

SKU:: AN300139P
Additional Names:: OLIG,RACK,BHLHB,OLIGO,bHLHe,PRKCBP,OLIG2,BHLHB1,OLIGO2,PRKCBP2,RACK17,bHLHe19
Application:: WB, IHC-P
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS
Immunogen:: A synthetic peptide corresponding to the N-terminus of the Human Olig-2.
Clone:: A1253
Uniprot:: Q13516
Synonyms:: basic domain, helix-loop-helix protein, class B, 1;BHLHB1;bHLHe19;class B basic helix-loop-helix protein 1;class E basic helix-loop-helix protein 19;human protein kinase C-binding protein RACK17;OLIGO2;oligodendrocyte lineage transcription factor 2;oligodendrocyte transcription factor 2;oligodendrocyte-specific bHLH transcription factor 2;PRKCBP2;protein kinase C-binding protein 2;Protein kinase C-binding protein RACK17;RACK17
Extra Details:: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 18 which has been suggested to play a role in learning deficits associated with Down syndrome.