AN300084P
Recombinant XPNPEP2 Monoclonal Antibody
Size
£361.80
Was £402.00
- SKU:
- AN300084P
- Additional Names:
- X-Pro Aminopeptidase,Xaa-Pro Aminopeptidase,Xpnpep,Aminoacylproline Aminopeptidase,mAmP,Membrane-Bound Aminopeptidase P,Membrane-Bound AmP,Membrane-Bound APP,Xaa-Pro Aminopeptidase 2,X-Pro Aminopeptidase 2,XPNPEP2
- Application:
- IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human XPNPEP2 protein
- Clone:
- A1194
- Uniprot:
- O43895
- Synonyms:
- AEACEI;aminoacylproline aminopeptidase;APP2;mAmP;membrane-bound aminopeptidase P;membrane-bound AmP;membrane-bound APP;X-Pro aminopeptidase 2;X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound;xaa-Pro aminopeptidase 2
- Extra Details:
- Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form of this enzyme (XPNPEP2) have been identified as products of two separate genes. XPNPEP2, the X-linked gene that encodes membranous aminopeptidase P (APP), has been reported to associate with APP activity. The membrane aminopeptidase P (XPNPEP2) is largely limited in distribution to endothelia and brush border epithelia. APP and XPNPEP2 contain homologous blocks of sequence common to members of the "pita bread-fold" protein family, of which Escherichia coli methionine aminopeptidase is the prototype. The C-2399A variant in XPNPEP2 is associated with reduced APP activity and a higher incidence of AE-ACEi. XPNPEP2 mRNA was detected in fibroblasts that carry the translocation, suggesting that this gene at least partially escapes X inactivation. XPNPEP2 is a candidate gene for premature ovarian failure (POF).
- Shipping Conditions:
- Blue Ice