Recombinant PIGR Monoclonal Antibody

Size

£170.10

Was £189.00

SKU:: AN300080P
Additional Names:: Hepatocellular carcinoma-associated protein TB,PIGR,Polymeric immunoglobulin receptor,Hepatocellular carcinoma-associated protein TB6,Secretory component,Poly-Ig receptor
Application:: IHC-P, IF, ICC
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS
Immunogen:: Recombinant Human PIGR protein
Clone:: A1190
Uniprot:: P01833
Synonyms:: hepatocellular carcinoma associated protein TB6;Hepatocellular carcinoma-associated protein TB6;poly-Ig receptor;polymeric immunoglobulin receptor
Extra Details:: The human polymeric immunoglobulin receptor (pIgR, also known as membrane secretory component) is an approximately 100 kDa type I transmembrane glycoprotein that is synthesized as a 764 amino acid (aa) precursor. It includes a signal sequence (aa 1-18), an extracellular region (aa 19-638), a transmembrane segment (aa 639-661), and a cytoplasmic domain (aa 662-764) . The extracellular region consists of five Ig-like domains and a sixth non-Ig domain that connects to the membrane region. pIgR is expressed on secretory epithelial cells of exocrine tissues. Immunoglobulin isotypes consist of two heavy (H) and two light (L) chains. F