AN300051L
Recombinant Phospho-IGF1R (Tyr1131)/Insulin Receptor B Beta (Tyr1146) Monoclonal Antibody
Size
£170.10
Was £189.00
- SKU:
- AN300051L
- Additional Names:
- JTK,IGF1R,CD221,IGFIR,IGFR,JTK13,CD221 antigen,IGF-1R,IGF-I R,IGF-I receptor,IGF-IR,insulin-like growth factor 1 receptor
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 10 mM sodium HEPES, 150 mM NaCl, 100 ug/mL protein protectant, 50% glycerol, pH 7.5
- Immunogen:
- A synthetic phosphopeptide corresponding to residues around Tyr1131 of the Human Phospho-IGF1R or Tyr1146 of the Human Insulin Receptor B Beta
- Clone:
- A1161
- Uniprot:
- P08069
- Synonyms:
- CD221;IGF-I receptor;IGFIR;IGFR;insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;JTK13;soluble IGF1R variant 1;soluble IGF1R variant 2
- Extra Details:
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice