AN200248P
IL12B Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN200248P
- Additional Names:
- NKSF,IL-12/IL-23 p,IL-12 subunit p,NK cell stimulatory factor chain,NK cell Stimulating Factor Chain,CLMF,CLMF p,IL12 p,CLMF2,Cytotoxic lymphocyte maturation factor 40 kDa subunit,Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40),IL12,IL-12 p40,IL12 p70,IL-12 p70,IL-12/IL-23 p40,NK cell Stimulating Factor Chain 2,p40,IL-12B,NKSF2,Interleukin-12 subunit beta,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,IL 12B,Il12b
- Application:
- IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Mouse
- Buffer:
- PBS
- Immunogen:
- Recombinant Mouse IL12B Protein
- Clone:
- A1102
- Uniprot:
- P43432
- Synonyms:
- CLMF p40;cytotoxic lymphocyte maturation factor 40 kDa subunit;Il-1;Il-12;IL-12 p40 subunit;IL-12 subunit p40;Il-12b;Il-12p40;IL-23 subunit p40;Il12p40;interleukin-12 p40 subunit;interleukin-12 subunit beta;p40
- Extra Details:
- Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.1 PublicationAssociates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
- Shipping Conditions:
- Blue Ice