AN200233P
PSGL-1/CD162 Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN200233P
- Additional Names:
- P selectin glycoprotein ligand,P-selectin glycoprotein ligand,CD 162,CD162,CD162 antigen,CLA,Cutaneous lymphocyte associated associated antigen,P selectin glycoprotein ligand 1,P selectin glycoprotein ligand 1 precursor,P-selectin glycoprotein ligand 1,PSGL 1,PSGL1,PSGL-1,Selectin P ligand,SELPL,SELPLG,PEN-5
- Application:
- IF, ICC
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human PSGL-1/CD162 Protein
- Clone:
- A1085
- Uniprot:
- Q14242
- Synonyms:
- CD162;CLA;cutaneous lymphocyte-associated associated antigen;P-selectin glycoprotein ligand 1;PSGL-1;PSGL1;Selectin P ligand
- Extra Details:
- P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
- Shipping Conditions:
- Blue Ice