AN200201P
IL-32 alpha/IL32A Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN200201P
- Additional Names:
- TAIFa,IL-32alpha,IL-32beta,IL-32delta,IL-32gamma,TAIFb,TAIFc,TAIFd,IL32,NK4,TAIF,IL 32alpha,IL 32beta,IL 32delta,IL 32gamma,IL-32,Interleukin 32,Interleukin 32 small,Interleukin 32 theta,Interleukin-32,interleukin-32 eta,Natural killer cell transcript 4,Natural killer cells protein 4,NK
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human IL-32 alpha/IL32A Protein
- Clone:
- A1053
- Uniprot:
- P24001
- Synonyms:
- IL-32alpha;IL-32beta;IL-32delta;IL-32gamma;interleukin-32;interleukin-32 eta;interleukin-32 small;interleukin-32 theta;natural killer cell transcript 4;natural killer cells protein 4;NK4;TAIF;TAIFa;TAIFb;TAIFc;TAIFd;tumor necrosis factor alpha-inducing factor
- Extra Details:
- IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.
- Shipping Conditions:
- Blue Ice