PGDH/PHGDH Monoclonal Antibody

Size

£311.40

Was £346.00

SKU:: AN200135P
Additional Names:: HEL-S,PHGDH,3-PGDH,3PGDH,HEL-S-113,NLS,NLS1,PDG,PGAD,PGD,PGDH,PHGDHD,SERA,PGDH3
Application:: Flow Cytometry, IF, ICC
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: Recombinant Human PGDH / PHGDH protein
Clone:: A983
Uniprot:: O43175
Synonyms:: 2-oxoglutarate reductase;3-PGDH;3-phosphoglycerate dehydrogenase;3PGDH;D-3-phosphoglycerate dehydrogenase;epididymis secretory protein Li 113;HEL-S-113;malate dehydrogenase;NLS;NLS1;PDG;PGAD;PGD;PGDH;PHGDHD;SERA
Extra Details:: This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.