AN200081P
SAE1 Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN200081P
- Additional Names:
- AOS,SUA,SAE,AOS1,SUA1,UBLE1A,SAE1,Activator of SUMO1,HSPC140,Sentrin/SUMO activating protein AOS1,SUMO 1 activating enzyme E1 N subunit,SUMO 1 activating enzyme subunit 1,SUMO-activating enzyme subunit 1,Ubiquitin like protein SUMO1 activating enzyme,Ubiquitin-like 1-activating enzyme E1A,UBL E1A
- Application:
- IF, ICC
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human SAE1 protein
- Clone:
- A929
- Uniprot:
- Q9UBE0
- Synonyms:
- activator of SUMO1;AOS1;HSPC140;sentrin/SUMO-activating protein AOS1;SUA1;SUMO-1 activating enzyme E1 N subunit;SUMO-1 activating enzyme subunit 1;SUMO-activating enzyme subunit 1;ubiquitin-like 1-activating enzyme E1A;ubiquitin-like protein SUMO-1 activating enzyme;UBLE1A
- Extra Details:
- SAE1 belongs to the ubiquitin-activating E1 family. It is a heterodimer that acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It functions as a UBLI E1 ligase mediating the ATP-dependent activation of UBL1. SAE1 binds with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. SAE1 also regulates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins.
- Shipping Conditions:
- Blue Ice