CD163 Monoclonal Antibody

Size

£311.40

Was £346.00

SKU:: AN200059P
Additional Names:: GHI/,SCARI,CD163,M130,MM130,SCARI1,ED2(rat),GHI/61,Hemoglobin/Haptoglobin Complex Receptor,macrophage-associated antigen,p155,RM3/1,GHI/61
Application:: IHC-P
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: E. coli-derived Human CD163 fragment
Clone:: A907
Uniprot:: Q86VB7
Synonyms:: hemoglobin scavenger receptor;M130;macrophage-associated antigen;MM130;SCARI1;scavenger receptor cysteine-rich type 1 protein M130
Extra Details:: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.