USP7/HAUSP Monoclonal Antibody

Size

£311.40

Was £346.00

SKU:: AN200056P
Additional Names:: TEF,USP,USP7,HAUSP,TEF1
Application:: IHC-P
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: Recombinant Human USP7 / HAUSP protein
Clone:: A904
Uniprot:: Q93009
Synonyms:: deubiquitinating enzyme 7;HAFOUS;HAUSP;Herpes virus-associated ubiquitin-specific protease;Herpesvirus-associated ubiquitin-specific protease;TEF1;ubiquitin carboxyl-terminal hydrolase 7;ubiquitin specific peptidase 7 (herpes virus-associated);ubiquitin specific protease 7 (herpes virus-associated);ubiquitin thioesterase 7;ubiquitin-specific-processing protease 7
Extra Details:: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM24, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.