BMP-4 Monoclonal Antibody

Size

£311.40

Was £346.00

SKU:: AN200042P
Additional Names:: OFC,DVR,MGC,ZGC,Bone morphogenetic protein,zbmp,MCOPS,BMP,BMP4,BMP2B,BMP2B1,MCOPS6,OFC11,ZYME,BMP 2B,BMP 4,BMP-2B,BMP-4,Bone morphogenetic protein 2B,Bone morphogenetic protein 4,MGC100779,zbmp-4,zgc:100779,DVR4
Application:: Flow Cytometry, IF, ICC
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: Recombinant Human BMP-4 protein
Clone:: A886
Uniprot:: P12644
Synonyms:: BMP2B;BMP2B1;bone morphogenetic protein 2B;bone morphogenetic protein 4;MCOPS6;OFC11;ZYME
Extra Details:: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.