AN200017P
RBP4 Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN200017P
- Additional Names:
- RET,PRO,Retinol-binding protein,MCOPCB,RBP4,MCOPCB10,RDCCAS,RBP-4,RET4,PRBP,RBP,Retinol-binding protein 4,Plasma retinol-binding protein,Cleaved into Plasma retinol-binding protein,Plasma retinol-binding protein 1-181,Plasma retinol-binding protein 1-179,Plasma retinol-binding protein(1-176),PRO2222
- Application:
- IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human RBP4 protein
- Clone:
- A861
- Uniprot:
- P02753
- Synonyms:
- MCOPCB10;plasma retinol-binding protein;PRBP;RBP;RDCCAS;retinol binding protein 4, plasma;retinol-binding protein 4;retinol-binding protein 4, interstitial
- Extra Details:
- Retinol (also known as vitamin A) is unstable and insoluble in the aqueous solution. However, retinol becomes quite stable and soluble in plasma due to its tight interaction with retinol-binding protein 4 (RBP4), also known as plasma retinol-binding protein. A prototypic member of the lipocalin superfamily, RBP4 has a beta -barrel structure with a well-defined cavity. It is secreted from the liver, a process requiring the availability of retinol. RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. The retinol-RBP4-TTR complex prevents the loss of RBP4 by filtration through the kidney and increases the stability of the retinol-RBP4 complex. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision.
- Shipping Conditions:
- Blue Ice