AN200016P
IL-1 beta Monoclonal Antibody
Size
£311.40
Was £346.00
- SKU:
- AN200016P
- Additional Names:
- IL1F,IL-1F,pro IL1F,IL-1,IL1-BETA,IL1F2,IL1 beta,IL1B,catabolin,IL-1B,pro Catabolin,pro IL1B,pro IL1F2,pro leukocytic endogenous mediator,pro leukocytic pyrogen,pro lymphocyte activating factor,pro mononuclear cell factor,IL-1F2,IL 1B,IL-1 beta
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- A synthetic peptide corresponding to the center region of the Human IL-1 beta
- Clone:
- A860
- Uniprot:
- P01584
- Synonyms:
- catabolin;IL-1;IL-1 beta;IL1-BETA;IL1beta;IL1F2;interleukin 1beta;interleukin-1 beta;preinterleukin 1 beta;pro-interleukin-1-beta
- Extra Details:
- Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
- Shipping Conditions:
- Blue Ice