PE Anti-Mouse Nos2(iNos) Antibody[W16030C]

Size

£153.90

Was £171.00

SKU:: AN00993D
Additional Names:: Nitric oxide synthase 2,nitric oxide synthase 2A,NOS2A,HEP-NOS,inducible nitric oxide synthase (iNOS),Nitric oxide synthase,inducible,Inducible NOS
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: Nos2
Clone:: W16030C
Uniprot:: P29477
Synonyms:: HEP-NOS;hepatocyte NOS;i-NOS;inducible nitric oxide synthase;inducible NO synthase;inducible NOS;INOS;MAC-NOS;macrophage NOS;N;nitric oxide synthase 2, inducible;nitric oxide synthase 2, inducible, macrophage;nitric oxide synthase 2A (inducible, hepatocytes);nitric oxide synthase, inducible;nitric oxide synthase, macrophage;No;NOS;NOS type II;Nos-2;NOS-II;NOS, type II;NOS2A;peptidyl-cysteine S-nitrosylase NOS2
Extra Details:: Nitric Oxide Synthase 2 (NOS2), also known as inducible NOS (iNOS), contains an N-terminal oxygenase domain and a C-terminal reductase domain, and functions to catalyze the formation of nitric oxide (NO) from L-arginine. NO is a reactive free radical which acts as a biologic messenger with diverse functions throughout the body, such as neurotransmission, antimicrobial, and antitumor activity. NOS2 is involved in inflammatory responses and enhances the synthesis of PGE2 and proinflammatory cytokines such as IL-6 and IL-8. The NOS2 gene is highly expressed in liver and is inducible by a combination of bacterial endotoxins and certain cytokines, including IL-1, IFNG Gamma and TNFA Alpha. NOS2 also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such as COX2.

Shipping Conditions:: Blue Ice