AN00950D
PE Anti-Human CD16 Antibody[B73.1]
Size
£104.40
Was £116.00
- SKU:
- AN00950D
- Additional Names:
- FcG GammaRIII,IGFR3,FCG3,FCGR3,FCGRIII,Fc gamma receptor,Fc gamma receptor 3,CD16a
- Application:
- Flow Cytometry
- Concentration:
- 5 ul/test
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- CD16
- Clone:
- B73.1
- Uniprot:
- P08637
- Synonyms:
- CD16;CD16A;CD16a antigen;Fc fragment of IgG, low affinity III, receptor for (CD16);Fc fragment of IgG, low affinity IIIa, receptor (CD16a);Fc gamma receptor III-A;Fc-gamma receptor III-2 (CD 16);Fc-gamma receptor IIIb (CD16);Fc-gamma RIII-alpha;FCG3;FcgammaRIIIA;FCGR3;FCGRIII;FCR-10;FCRIII;FCRIIIA;IGFR3;igG Fc receptor III-2;IMD20;immunoglobulin G Fc receptor III;low affinity immunoglobulin gamma Fc region receptor III-A;low affinity immunoglobulin gamma receptor III-a Fc fragment;neutrophil-specific antigen NA
- Extra Details:
- CD16 is known as low affinity IgG receptor III (FcG GammaRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcG GammaRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, a subset of T cells and placental trophoblasts in humans. CD16b (FcG GammaRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
- Shipping Conditions:
- Blue Ice