APC Anti-Mouse CD44 Antibody[NIM-R8]

Size

£72.90

Was £81.00

SKU:: AN00917E
Additional Names:: Hermes,Pgp-1,H-CAM,HUTCH-1,ECMR III,gp85,Ly-24
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD44
Clone:: NIM-R8
Uniprot:: P15379
Synonyms:: AU023126;AW121933;AW146109;CD44 antigen;ECMR-III;extracellular matrix receptor III;GP90 lymphocyte homing/adhesion receptor;HERM;HERMES;hermes antigen;HUTCH-I;hyaluronate receptor;Ly-2;Ly-24;lymphocyte antigen 24;Pgp;Pgp-1;PGP-I;phagocytic glycoprotein 1;phagocytic glycoprotein I
Extra Details:: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.