APC Anti-Mouse VISTA Antibody[MIH63]

Size

£89.10

Was £99.00

SKU:: AN00875E
Additional Names:: PD-1 homolog,Dies1,B7-H5
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: VISTA
Clone:: MIH63
Uniprot:: Q9D659
Synonyms:: 4632428N05Rik;Die;Dies1;differentiation of ESCs 1;PD-1;PD-1H;platelet receptor Gi24;V;V-set domain-containing immunoregulatory receptor;V-set immunoregulatory receptor;V-type immunoglobulin domain-containing suppressor of T-cell activation;VISTA
Extra Details:: PD-1H, also known as VISTA, is a 309 aa type I transmembrane protein that is composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and natural killer cells (NK). It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants due to its ability to preferentially suppress CD4+ T cell-mediated immunity.