APC Anti-Mouse MERTK Antibody[2B10C42]

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£153.90

Was £171.00

SKU:: AN00871E
Additional Names:: Mer,Eyk,Nyk,nmf12
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: MERTK
Clone:: 2B10C42
Uniprot:: Q60805
Synonyms:: c-mer proto-oncogene tyrosine kinase;Eyk;Me;Mer;nmf1;nmf12;Ny;Nyk;proto-oncogene c-Mer;proto-oncogene tyrosine-protein kinase Mer;receptor tyrosine kinase MerTK;Tyro 12;tyrosine-protein kinase Mer
Extra Details:: MerTK (Mer) is a member of the TAM (TYRO3/AXL/MerTK) family. It is a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. MerTK is mainly expressed by macrophages, monocytes, and dendritic cells. Its ligands are LGALS3, TUB, TULP1, and GAS6. MerTK is involved in the regulation of TLR signaling, efferocytosis, phagocytosis, cell survival, macrophage migration, and the inhibition of inflammation.