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AN007170L

Cathepsin L Polyclonal Antibody

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£120.60

Was £134.00

SKU:
AN007170L
Additional Names:
CATL,CATL1,CTSL,CTSL1,Cathepsin L1,Cathepsin L1 light chain,CathepsinL,FLJ31037,MEP,MGC123162,Major excreted protein,cathepsin L,cb15,ctsl1b,hgg1
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human Cathepsin L protein expressed by Mammalian
Uniprot:
P07711
Synonyms:
Cathepsin L;cathepsin L1;CATL;CTSL1;major excreted protein;MEP;procathepsin L
Extra Details:
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.
Shipping Conditions:
Blue Ice