AN00652E
APC Anti-Rat CD172a Antibody[OX-41]
Size
£70.20
Was £78.00
- SKU:
- AN00652E
- Additional Names:
- SIRPa,PTPNS1,BIT,MFR,p84,CD172 antigen-like family member A
- Application:
- Flow Cytometry
- Concentration:
- 5 ul/test
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Rat
- Buffer:
- PBS
- Immunogen:
- CD172a
- Clone:
- OX-41
- Uniprot:
- P97710
- Synonyms:
- AI835480;Bi;Bit;brain Ig-like molecule with tyrosine-based activation motifs;Brain immunoglobulin like protein with tyrosine - based activation motifs;brain immunological-like with tyrosine-based motifs;CD172;CD172 antigen-like family member A;CD172a;Idd13.2;inhibitory receptor SHPS-1;macrophage fusion receptor;macrophage membrane protein MFP150;mSIRP-alpha1;myD-1 antigen;P8;P84;protein tyrosine phosphatase, non-receptor type substrate 1;Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1);Pt;Ptpns1;SHP;SHP substrate 1;SHP-1;SHPS-1;signal-regulatory protein alpha-1;SIRP;sirp-alpha-1;tyrosine-protein phosphatase non-receptor type substrate 1
- Extra Details:
- Rat CD172a, also known as a signal-regulatory protein (SIRP), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.
- Shipping Conditions:
- Blue Ice