PE Anti-Mouse CD45 Antibody[I3/2.3]

Size

£68.40

Was £76.00

SKU:: AN00630D
Additional Names:: T200,Ly-5,LCA
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD45
Clone:: I3/2.3
Uniprot:: P06800
Synonyms:: B220;Cd45;CD45R;L-CA;leukocyte common antigen;loc;Ly-;Ly-5;lymphocyte antigen 5;lymphocyte common antigen;Lyt-;Lyt-4;receptor-type tyrosine-protein phosphatase C;T200
Extra Details:: CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.