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AN005890L

PDGF-AA Polyclonal Antibody

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£120.60

Was £134.00

SKU:
AN005890L
Additional Names:
PDGF A,PDGF A chain,Platelet derived growth factor alpha isoform 2 preproprotein,Platelet derived growth factor alpha polypeptide,PDGF1,PDGF-A,PDGFA,PDGF subunit A,PDGF-1,PDGF-AA,PDGFAA,Platelet Derived Growth Factor AA,Platelet derived growth factor alpha chain,Platelet-derived growth factor subunit A,Platelet-derived growth factor A chain,Platelet-derived growth factor alpha polypeptide
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human PDGF-AA protein expressed by E.coli
Uniprot:
P04085
Synonyms:
PDGF A-chain;PDGF subunit A;PDGF-1;PDGF-A;PDGF1;Platelet-derived growth factor A chain;platelet-derived growth factor A-chain;platelet-derived growth factor alpha chain;platelet-derived growth factor alpha polypeptide;platelet-derived growth factor subunit A
Extra Details:
The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of four homodimeric proteins, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD, and one heterodimeric protein, PDGF-AB. Members of this protein family act mainly on connective tissue. The dimeric isoforms of PDGF are expressed by different cell types and at different times during embryonic development. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms that contain a PDGF/VEGF cysteine knot domain. Only PDGF-C and PDGF-D, also named spinal cord-derived growth factors SCDGF and SCDGF-B, also contain an N-terminal CUB domain. Mature PDGF dimers bind and induce the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta).
Shipping Conditions:
Blue Ice