PE Anti-Mouse TNFA Alpha Antibody[XT3.11]

Size

£60.30

Was £67.00

SKU:: AN00567D
Additional Names:: Tumor necrosis factor-A Alpha,Cachectin,Necrosin,Macrophage cytotoxic factor,Differentiation inducing factor,TNFSF-2,TNF-a,TNF-alpha
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: TNF-α
Clone:: XT3.11
Uniprot:: P06804
Synonyms:: cachectin;DI;DIF;Tn;TNF-;TNF-a;TNF-alpha;Tnfa;TNFalpha;Tnfs;Tnfsf1a;TNFSF2;Tnlg1f;tumor necrosis factor;tumor necrosis factor ligand 1f;tumor necrosis factor ligand superfamily member 2;tumor necrosis factor-alpha
Extra Details:: TNF-A Alpha is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-A Alpha. Monomeric mouse TNF-A Alpha is a 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD. TNF-A Alpha forms multimeric complexes, stable trimers are most common in solution. A 26 kD membrane form of TNF-A Alpha has also been described. TNF-A Alpha binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorrhagic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.