FITC Anti-Human CD62L Antibody[DREG.55]

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£128.70

Was £143.00

SKU:: AN00477C
Additional Names:: Integrin B Beta2 subunit,LFA -1 B Beta subunit,B Beta2 integrin,ITGB2,b2 integrin,beta 2 integrin
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD62L
Clone:: DREG.55
Uniprot:: P14151
Synonyms:: CD62 antigen-like family member L;CD62L;gp90-MEL;L-selectin;LAM1;LECAM1;LEU8;Leukocyte adhesion molecule 1;leukocyte surface antigen Leu-8;leukocyte-endothelial cell adhesion molecule 1;LNHR;LSEL;LYAM1;lymph node homing receptor;lymphocyte adhesion molecule 1;pln homing receptor;PLNHR;TQ1
Extra Details:: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.