APC Anti-Mouse CD49d Antibody[R1-2]

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£70.20

Was £78.00

SKU:: AN00422E
Additional Names:: A Alpha4 integrin,VLA-4 A Alpha chain,integrin A Alpha4,ITGA4
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD49d
Clone:: R1-2
Uniprot:: Q00651
Synonyms:: CD49 antigen-like family member D;CD49D;integrin alpha-4;integrin alpha-IV;integrin alpha4B;Itga4B;LPAM subunit alpha;lymphocyte Peyer patch adhesion molecules subunit alpha;VLA-4 receptor, alpha 4 subunit;VLA-4 subunit alpha
Extra Details:: CD49d is a 150 kD glycoprotein, also known as A Alpha4 integrin or VLA-4 A Alpha chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two B Beta chains, B Beta1 (CD29) or B Beta7, to form the VLA-4 (integrin A Alpha4B Beta1) or LPAM-1 (integrin A Alpha4B Beta7) complexes. CD49d plays a critical role in adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin.