AN003440
Purified Anti-Mouse/Human GAL3 Antibody[M3/38], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- AN003440
- Additional Names:
- MAC,Galactose-specific lectin,Galactoside-Binding Soluble,Galectin,Lectin L,GAL,CBP,LGALS3,CBP35,GAL3,GALBP,GALIG,L31,LGALS2,MAC2,Galactoside-Binding Soluble 3,Lectin,Galectin-3,Gal-3,L-31,35 kDa lectin,CBP 35,Galactose-specific lectin 3,IgE-binding protein,Laminin-binding protein,Lectin L-29,Mac-2 antigen,Carbohydrate binding protein 35,Carbohydrate-binding protein 35,galactose binding,galactoside binding soluble 3,Galactoside-binding protein,galectin 3,Galectin 3 internal
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Human, Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse GAL3 protein
- Clone:
- M3/38
- Uniprot:
- P17931
- Synonyms:
- 35 kDa lectin;advanced glycation end-product receptor 3;carbohydrate-binding protein 35;CBP35;epididymis secretory sperm binding protein;GAL3;galactose-specific lectin 3;Galactoside-binding protein;GALBP;galectin-3;GALIG;IgE-binding protein;L-31;L31;laminin-binding protein;lectin L-29;lectin, galactoside-binding, soluble, 3;LGALS2;MAC-2 antigen;MAC2
- Extra Details:
- Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice