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AN00327E

APC Anti-Mouse CD6 Antibody[OX-129]

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£85.50

Was £95.00

SKU:
AN00327E
Additional Names:
CD6,TP120
Application:
Flow Cytometry
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Host:
Rat
Reactivities:
Mouse
Buffer:
PBS
Immunogen:
CD6
Clone:
OX-129
Uniprot:
Q61003
Synonyms:
T-cell differentiation antigen CD6
Extra Details:
CD6, a 100 kD monomeric T cell surface glycoprotein, is a member of the scavenger receptor cysteine-rich protein superfamily. It is expressed on mouse thymocytes and splenic T cells and neurons, but not on splenic B cells. CD6 has a long cytoplasmic tail in mice, with two proline-rich domains that interact with the -SH3 domain binding sequence. CD6 binding to its ligand, CD166 (ALCAM), serves as a costimulatory molecule through its interaction with SLP-76. CD6 mediated signaling may contribute to thymocyte survival and functional avidity in mice and men.
Shipping Conditions:
Blue Ice