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AN00326D

PE Anti-Human/Monkey CD180 Antibody[MHR73-11]

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£127.80

Was £142.00

SKU:
AN00326D
Additional Names:
CD180,Radio-protective 105-kD protein,RP105
Application:
Flow Cytometry
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Host:
Mouse
Reactivities:
Human
Buffer:
PBS
Immunogen:
CD180
Clone:
MHR73-11
Uniprot:
Q99467
Synonyms:
CD180 antigen;LY64;Ly78;lymphocyte antigen 64;lymphocyte antigen-64, radioprotective, 105kDa;radioprotective 105 kDa protein;RP105
Extra Details:
CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
Shipping Conditions:
Blue Ice