AN002890
Purified Anti-Human CD85j Antibody[GHI/75], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- AN002890
- Additional Names:
- LILRB,ILT,LIR,MIR,LILRB1,CD85J,ILT-2,ILT2,LIR-1,LIR1,MIR-7,MIR7,PIR-B,PIRB, ILT2, LILRB1,CD85,CD85 antigen,CD85 antigen like family member J,CD85 antigen-like family member J,CD85j antigen,Ig like transcript 2,ILT 2,immunoglobulin like transcript 2,Immunoglobulin-like transcript 2,leukocyte Ig like receptor 1,leukocyte immunoglobulin like receptor,Leukocyte immunoglobulin like receptor 1,leukocyte immunoglobulin like receptor subfamily B member 1,Leukocyte immunoglobulin like receptor
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Human CD85j protein
- Clone:
- GHI/75
- Uniprot:
- Q8NHL6
- Synonyms:
- CD85 antigen-like family member J;CD85J;Ig-like transcript 2;ILT-2;ILT2;immunoglobulin heavy chain variable region;Immunoglobulin-like transcript 2;leucocyte Ig-like receptor B1;leukocyte immunoglobulin-like receptor subfamily B member 1;leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1;LIR-1;LIR1;MIR-7;MIR7;monocyte/macrophage immunoglobulin-like receptor 7;myeloid inhibitory receptor 7;PIR-B;PIRB
- Extra Details:
- This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice