APC Anti-Human CD14 Antibody[H332-1B10]

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£78.30

Was £87.00

SKU:: AN00213E
Additional Names:: LPS receptor
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD14
Clone:: H332-1B10
Uniprot:: P08571
Synonyms:: monocyte differentiation antigen CD14;myeloid cell-specific leucine-rich glycoprotein
Extra Details:: CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokines expression in monocytes and neutrophils.