Y04921H
Recombinant Human IL-1B
Size
£391.00
- SKU:
- Y04921H
- Additional Names:
- IL1-BETA，IL-1，Interleukin-1beta，IL-1B，IL-1β，IL-1 β，IL1beta，Interleukin 1beta，Catabolin，IL-1 beta，IL1B，Interleukin 1 Beta，IL1F2，Pro-Interleukin-1-Beta，Preinterleukin 1 Beta，Interleukin-1 Beta
- Application:
- Functional Assay
- Molecular Weight:
- 17.4 kDa
- Purity:
- ≥95% by SDS-PAGE
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Host:
- E. coli
- ABP:
- No Import Docs
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
- Format:
- Lyophilized powder
- Extra Details:
- IL-1β (Interleukin-1β) is a key pro-inflammatory cytokine that plays a central role in immune regulation, inflammatory responses, and cellular signaling. The mature form of IL-1β adopts a β-trefoil structure composed of 12 β-strands and interacts via surface residues with the IL-1R1 receptor to initiate downstream signaling. IL-1β stimulates the secretion of other inflammatory factors, such as TNF-α and IL-6, as well as chemokines, thereby mimicking an in vivo inflammatory environment. Additionally, it activates immune cells by promoting T cell proliferation, B cell differentiation, and enhancing the antigen-presenting capacity of macrophages and dendritic cells.
- Shipping Conditions:
- Blue Ice