Y04701
Recombinant Human VEGF165
Size
£381.00
- SKU:
- Y04701
- Additional Names:
- Vascular Endothelial Growth Factor，VEGF-A，MVCD1，Vascular endothelial growth factor A，VEGF，VEGFA，VPF，Vascular Endothelial Growth Factor A165，Vascular permeability factor
- Application:
- Functional Assay
- Molecular Weight:
- 19.1 kDa
- Purity:
- ≥95% by SDS-PAGE
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Host:
- Hamster
- ABP:
- No Import Docs
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4
- Format:
- Lyophilized powder
- Extra Details:
- VEGF165 (Vascular Endothelial Growth Factor 165), one of the major isoforms of VEGF-A, functions as a disulfide-linked homodimer and plays a critical role in angiogenesis and cell culture. It activates the VEGFR2/PI3K/AKT signaling pathway to inhibit apoptosis and is commonly used to sustain the proliferative capacity of human umbilical vein endothelial cells (HUVECs) and microvascular endothelial cells in vitro. In Matrigel-based tube formation assays, VEGF165 stimulates endothelial cells to form tubular structures, thereby mimicking the process of angiogenesis. In stem cell differentiation systems, it can induce commitment to endothelial cell lineages or support the development of vascular-like structures.
- Shipping Conditions:
- Blue Ice