Y04201N
Recombinant Human TGF-β1
Size
£466.00
- SKU:
- Y04201N
- Additional Names:
- Latency-Associated Peptide，IBDIMDE，Transforming Growth Factor beta1，Prepro-Transforming Growth Factor Beta-1，TGF-Beta-1，Transforming Growth Factor， Beta 1，CED，TGFB，DPD1，TGFB1，Transforming Growth Factor Beta-1 Proprotein，Camurati-Engelmann Disease，LAP，TGFbeta，Transforming Growth Factor Beta 1，Diaphyseal Dysplasia 1， Progressive，TGF-Beta1
- Application:
- Functional Assay
- Molecular Weight:
- 12.8 kDa
- Purity:
- ≥95% by SDS-PAGE
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Host:
- Hamster
- ABP:
- No Import Docs
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing 0.085% TFA, 30% ACN, 5% mannitol, pH 2.5
- Format:
- Lyophilized powder
- Extra Details:
- TGF-β1 (Transforming Growth Factor-β1) is a multifunctional cytokine belonging to the TGF-β superfamily. It inhibits the growth of most epithelial, endothelial, and hematopoietic cells by inducing cell cycle arrest in the G1 phase. In stem cell culture, TGF-β1 can direct the differentiation of mesenchymal stem cells into osteoblasts, chondrocytes, or adipocytes. In organoid culture systems, it regulates extracellular matrix (ECM) formation and influences tissue organization. Additionally, TGF-β1 exhibits immunomodulatory effects by suppressing the activation of T cells, B cells, NK cells, and macrophages, thereby reducing inflammatory responses. In co-culture systems—such as those involving immune and tumor cells—TGF-β1 can help mimic an immune-suppressive microenvironment.
- Shipping Conditions:
- Blue Ice