Y03021H
Recombinant Human LIF
Size
£360.00
- SKU:
- Y03021H
- Additional Names:
- LIF, CDF, DIA, HILDA, MLPLI
- Application:
- Functional Assay
- Molecular Weight:
- 19.7 kDa
- Purity:
- ≥95% by SDS-PAGE
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Host:
- E. coli
- ABP:
- No Import Docs
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
- Format:
- Lyophilized powder
- Extra Details:
- LIF (Leukemia Inhibitory Factor) is a pleiotropic cytokine belonging to the IL-6 family. As a secreted glycoprotein, it activates downstream signaling pathways by binding to the LIFR/gp130 receptor complex and plays a critical role in cell culture, particularly in stem cell maintenance. Its primary function is to sustain pluripotency in mouse embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). In other stem cell contexts, LIF promotes the survival and proliferation of neural stem cells and, in combination with factors such as SCF and IL-3, helps maintain the stemness of hematopoietic stem cells.
- Shipping Conditions:
- Blue Ice