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Y01421H

Recombinant Human GDNF

Size

£462.00

SKU:
Y01421H
Additional Names:
Glial Cell Line-Derived Neurotrophic Factor,NTF,GDNF
Application:
Functional Assay
Molecular Weight:
15.2 kDa
Purity:
≥95% by SDS-PAGE
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Host:
E. coli
ABP:
No Import Docs
Formulation:
Lyophilized from a 0.22 um filtered solution containing 20 mM Sodium Citrate, 5% Mannitol, pH 2.5
Format:
Lyophilized powder
Extra Details:
GDNF (Glial Cell Line-Derived Neurotrophic Factor) is an important neurotrophic factor belonging to the TGF-β superfamily. Initially isolated from a rat glial cell line, it has become a research focus due to its remarkable protective effects on dopaminergic neurons, showing potential therapeutic value especially in the treatment of Parkinson's disease. GDNF is also involved in the cultivation and directed differentiation of stem cells, and is often used in combination with factors such as SHH and FGF8 to induce the differentiation of embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) into dopaminergic neurons.
Shipping Conditions:
Blue Ice