Y00921H
Recombinant Human FGF-4
Size
£447.00
- SKU:
- Y00921H
- Additional Names:
- FGF-4, Fibroblast growth factor 4, HST, HST-1
- Application:
- Functional Assay
- Molecular Weight:
- 19.3 kDa
- Purity:
- ≥95% by SDS-PAGE
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Host:
- E. coli
- ABP:
- No Import Docs
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4
- Format:
- Lyophilized powder
- Extra Details:
- FGF-4 (Fibroblast Growth Factor 4), a member of the FGF family, is a secreted glycoprotein that activates downstream signaling pathways (such as MAPK and PI3K-AKT) by binding to its receptors (FGFRs). It promotes cell proliferation, differentiation, migration, and survival, playing a central role in embryonic development, mesoderm formation, and stem cell maintenance. In stem cells, it helps maintain pluripotency; for example, FGF-4 and LIF (Leukemia Inhibitory Factor) act synergistically to sustain the undifferentiated state of mouse embryonic stem cells (ESCs). Additionally, FGF-4 can promote the differentiation of specific cell types and is used in the culture of primary cells.
- Shipping Conditions:
- Blue Ice